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Recettore D₄ della dopamina
Proteine
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Il recettore della dopamina D₄ è un recettore accoppiato alla proteina G simile a D2 della dopamina codificato dal gene DRD4 sul cromosoma 11 in 11p15.5.
La struttura di DRD4 è stata segnalata in complesso con il farmaco antipsicotico nemonapride.... Wikipedia (inglese)
The dopamine receptor D4 is a dopamine D2-like G protein-coupled receptor encoded by the DRD4 gene on chromosome 11 at 11p15.5.
DRD4 influences the postsynaptic action of dopamine and is implicated in many neurological processes, exhibits polymorphism and is one of the most studied genes ...
11 apr 2024 · Dopamine D4 receptor is down-regulation in hyperglycemia-induced endothelial dysfunction. D4 receptor agonist greatly improved endothelial cell ...
Se contribuisce all'effetto antipsicotico in pazienti schizofrenici il blocco recettoriale D3, questo effetto sarebbe da ascrivere all'azione su recettori ...
20 nov 2008 · These D4R-mutant mice may be useful in studying dopamine/neurotransmitter function, drug addiction, Parkinson's disease, and schizophrenia or ...
10 apr 2019 · Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and ...
The Dopamine Receptor D4 Gene (DRD4) and Financial Risk-Taking
www.frontiersin.org › fnbeh.2018.00034
14 feb 2018 · The DRD4, a dopamine D4 receptor gene, is located near the telomere of chromosome 11p and contains a 48-bp Variable Number Tandem Repeat (VNTR) ...
23 ago 2002 · A meta-analytical review of 20 studies (n = 3907) of the association between DRD4 polymorphism and novelty seeking suggests the following ...
The dopamine D4 receptor gene (DRD4) is one of the five known G protein-coupled receptors for which dopamine is the primary neurotransmitter. The gene is ...
Polymorphisms of the dopamine receptor D4 (DRD4) gene, dopamine transporter (DAT1) gene, and catechol-O-methyltransferase (COMT) gene showed significant ...