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Lofexidine
Medication
Lofexidine, sold under the brand name Lucemyra among others, is a medication historically used to treat high blood pressure; today, it is more commonly used to help with the physical symptoms of opioid withdrawal. It is taken by mouth. It is an... Wikipedia
ATC code: N07BC04 (WHO)
Bioavailability: >90%
Elimination half-life: 11 hours
Metabolism: Liver (glucuronidation)
Protein binding: 80–90%
UNII: UI82K0T627
People also ask
Is lofexidine the same as clonidine?
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How effective is lofexidine?
Aug 15, 2018 · Lofexidine is used to manage opioid withdrawal symptoms (e.g., sick feeling, stomach cramps, muscle spasms or twitching, cold sensation, ...
Aug 10, 2018 · Lofexidine may be an option before starting extended-release naltrexone. One group of patients who do require medically supervised withdrawal ...
Lofexidine, an alpha-2 agonist, can be used to manage acute withdrawal symptoms before starting maintenance treatment with either methadone or buprenorphine.
Mar 15, 2019 · Lofexidine has been shown to be as effective as clonidine at controlling some of the symptoms of withdrawal from opioid use.
Lofexidine is used to help reduce withdrawal symptoms (eg, stomach cramps, muscle spasms or twitching, yawning, runny eyes, trouble sleeping, pounding of the ...
LUCEMYRA is the first & only FDA-approved, non-opioid, treatment for relief of multiple symptoms of opioid withdrawal after abrupt discontinuation in adults ...
Lofexidine, sold under the brand name Lucemyra among others, is a medication historically used to treat high blood pressure; today, it is more commonly used ...
Lofexidine is a centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid ...
Apr 10, 2023 · Lofexidine works by blocking the release of norepinephrine, a hormone similar to adrenaline that contributes to opioid withdrawal symptoms.
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For informational purposes only. Consult your local medical authority for advice.