Biguanide
Compounds
Biguanide is the organic compound with the formula HN(C(NH)NH₂)₂. It is a colorless solid that dissolves in water to give highly basic solution. These solutions slowly hydrolyse to ammonia and urea. Wikipedia
Formula: C2H7N5
Beilstein Reference: 507183
Gmelin Reference: 240093
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May 22, 2023 · Biguanides are a type of oral diabetes medication. They help manage Type 2 diabetes by lowering blood glucose levels.
Jun 30, 2022 · In general, biguanides are believed to exert their antitumor properties by two main mechanisms: direct, by acting directly on the tumor cells ...
Metformin, a biguanide, is considered in EASD and ADA to be a first-line glucose-lowering agent for patients with type 2 diabetes.
It acts as an insulin sensitizing agent, probably through activation of adenosine monophosphate–dependent kinase in liver and muscle tissue. Biguanide drugs are ...
The drug has a two-fold mechanism of action: it enhances the peripheral muscle glucose uptake and utilization, and inhibits glucose release from the liver.
Biguanides are a class of antidiabetic medications, sometimes referred to as non-sulfonylureas, used to treat Type 2 diabetes.
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