Triptolide
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Triptolide là một epoxit diterpenoid được tạo ra bởi cây nho thần sấm, Tripterygium wilfordii. Nó có các hoạt động in vitro và in vivo chống lại các mô hình chuột mắc bệnh thận đa nang và ung thư tuyến tụy, nhưng các đặc tính vật lý và độc tính... Wikipedia (tiếng Anh)
Phân loại: Epoxit
Công thức: C20H24O6
Mọi người cũng hỏi
What is the drug triptolide used for?
What is the mechanism of action of triptolide?
How does triptolide inhibit transcription?
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Triptolide is a diterpenoid epoxide which is produced by the thunder god vine, Tripterygium wilfordii. It has in vitro and in vivo activities against mouse ...
24 thg 5, 2021 · Triptolide, an abietane-type diterpenoid isolated from Tripterygium wilfordii Hook. F., has significant pharmacological activity.
Triptolide (TP) is a diterpenoid triepoxide obtained from Tripterygium wilfordii. It is effective against psoriasis due to its strong inhibitory action on DCs, ...
8 thg 4, 2019 · Triptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and trafficking.
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Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It functions as a NF-κB inhibitor with dual ...
7 thg 11, 2021 · It is a potential drug for the treatment of various autoimmune diseases, but its clinical application is still restricted due to severe toxicity ...
Triptolide, the active diterpene in the traditional Chinese medicine Lei Gong Teng, induces cellular calcium release through a PC2–dependent pathway, arrests ...
9 thg 11, 2020 · Triptolide suppresses super-enhancer activation marks and causes transcriptional downregulation of associated genes in pancreatic cancer cells ...
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Triptolide is a natural product derived from the Chinese plant Tripterygium wilfordii, is reported to exhibit antitumor effects in a broad range of cancers.