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Filaggrin

Protein
Filaggrin là một protein dạng sợi liên kết với các sợi keratin trong tế bào biểu mô. Mười đến mười hai đơn vị filaggrin được thủy phân sau dịch mã từ một protein tiền thân profilaggrin lớn trong quá trình biệt hóa cuối cùng của các tế bào biểu bì.... Wikipedia (tiếng Anh)
Phân loại: Protein
Mọi người cũng hỏi
22 thg 4, 2009 · Filaggrin specifically interacts with intermediate filaments, particularly keratins, but not with other components of the cytoskeleton such as ...
8 thg 12, 2011 · The filaggrin story demonstrates how the study of a monogenic disorder can provide insight into complex trait disease and the striking ...
Filaggrin từ eczema.org
If you have atopic eczema, you really need to know about filaggrin. This large protein was first discovered by Beverly A. Dale, back in 1977. However it was not ...
1 thg 10, 2017 · Filaggrin plays an important role in the skin's barrier function. It brings together structural proteins in the outermost skin cells to form ...
Filaggrin is a filament-associated protein that binds to keratin fibers in epithelial cells and plays an essential role in terminal differentiation of ...
17 thg 2, 2020 · The genetic background of Atopic Dermatitis (AD) with chronic pruritus is complex. Filaggrin (FLG) is an essential gene in the epidermal ...
Filaggrin từ www.sciencedirect.com
Filaggrin is an essential protein for the correct formation and function of the skin barrier. Mutations in the FLG gene are responsible for ichthyosis vulgaris ...
Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema. Nat Genet. 2007; 39 ...
24 thg 9, 2023 · The role of filaggrin in atopic dermatitis and allergic disease. ... Its precursor, profilaggrin, is encoded for by the FLG gene on chromosome ...