NOD2 (Nucleotide Binding Oligomerization Domain Containing 2) is a Protein Coding gene. Diseases associated with NOD2 include Blau Syndrome and Inflammatory Bowel Disease 1. Among its related pathways are MyD88 dependent cascade initiated on endosome and SARS-CoV-2 Infection.
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1 dic 2017 · The NOD2 gene (previously known as CARD15) provides instructions for making a protein that plays an important role in immune system function ...
11 abr 2024 · NOD2 is crucial to control intracellular infection caused by Leishmania spp. NOD2 receptor is important for Leishmania recognition, the control ...
NOD2 plays an important role in the immune system. It recognizes bacterial molecules (peptidoglycans) and stimulates an immune reaction.
12 feb 2018 · NOD2 has been localized in inflamed areas of atherosclerotic lesions and is overexpressed in endothelial cells delimiting the lumen of diseased ...
NOD2. NOD2 is an intracellular pattern recognition receptor that, after activation by bacterial peptidoglycan or muramyl dipeptide (MDP), activates the ...
10 jun 2016 · NOD2, also known as NLRC2 or CARD15, belongs to the NLRC subfamily of NLRs. NOD2 possesses two tandem CARDs that function as an effector domain ...
Acts as a regulator of appetite by sensing MDP in a subset of brain neurons: microbiota-derived MDP reach the brain, where they bind and activate NOD2 in ...
NOD2 belongs to the nucleotide-binding oligomerization domain (NOD)-like receptor family of PRRs (summary by Keestra-Gounder et al., 2016). ▻ Cloning and ...