Dextropropoxyphene
Drug
Addiction liability: Low
AHFS/Drugs.com: Monograph
Bioavailability: 40%
Elimination half-life: 6–12 hours; 30–36 hours (active metabolite, nordextropropoxyphene)
Excretion: Urine (major), breastmilk (minor)
Metabolism: Liver-mediated, CYP3A4-mediated N-demethylation (major), aromatic hydroxylation (minor) and ester hydrolysis (minor)
Pregnancy category: AU: C