Mona Simpson
The Simpsons character
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Mona J. Simpson is a fictional guest character in the animated television series The Simpsons. She is voiced most prominently by Glenn Close, but has also been voiced by Maggie Roswell, Tress MacNeille, and Pamela Hayden. Wikipedia
Spouse: Grampa Simpson
Children: Homer Simpson
Created by: Jeff Martin; Richard Appel; Matt Groening
First appearance: "Oh Brother, Where Art Thou?"; The Simpsons; February 21, 1991
Last appearance: "Mothers and Other Strangers"; November 28, 2021
Voiced by: Maggie Roswell (1991–1994); Glenn Close (1995–2021); Tress MacNeille ("D'oh-in' in the Wind")