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Ebastine

Medicinal
Ebastine is a H₁ antihistamine with low potential for causing drowsiness. It does not penetrate the blood–brain barrier to a significant amount and thus combines an effective block of the H₁ receptor in peripheral tissue with a low incidence of... Wikipedia
AHFS/Drugs.com: International Drug Names
Elimination half-life: 15 to 19 hours (carebastine)
Metabolism: Hepatic (CYP3A4-mediated), to carebastine
Routes of administration: Oral