Talk To Your Doctor About KADCYLA®. View Full Safety, Prescribing Info & Boxed Warning. Discover How KADCYLA® Is Thought To Work And Find Financial Support & Patient Resources.
Info On KADCYLA® As A Treatment Option. See Full Safety, Prescribing Info & Boxed Warning. Review KADCYLA® Clinical Trial Data. See Full Safety, Prescribing Info & Boxed Warnings.
Trastuzumab emtansine
Drug
Trastuzumab emtansine, sold under the brand name Kadcyla, is an antibody-drug conjugate consisting of the humanized monoclonal antibody trastuzumab covalently linked to the cytotoxic agent DM1. Wikipedia
AHFS/Drugs.com: Monograph
Elimination half-life: 4 days
License data: EU EMA: by INN; US DailyMed: Trastuzumab_emtansine; US FDA: Kadcyla
Metabolism: Liver (CYP3A4/3A5-mediated)
Other names: ado-trastuzumab emtansine, trastuzumab-DM1, T-DM1
Pregnancy category: : AU: D;
Protein binding: 93% (in vitro)