Duke of Osuna is a Spanish noble title that was first awarded in 1562 by King Philip II of Spain to Pedro Girón de la Cueva. Pedro was also Viceroy of Naples, Ambassador in Portugal and 5th Count of Ureña.
The fortunes of the town of Osuna started... Wikipedia
First holder: Pedro Téllez-Girón y de la Cueva, 1st Duke of Osuna