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Great Chicago Fire

The Great Chicago Fire was a conflagration that burned in the American city of Chicago during October 8–10, 1871. The fire killed approximately 300 people, destroyed roughly 3.3 square miles of the city including over 17,000 structures, and left... Wikipedia
Dates: Oct 8, 1871 – Oct 10, 1871
Location: Chicago
Deaths: 300 (estimate)
Burned area: 2,112 acres (8.55 km2)
Damage: $222 million (1871 USD); (approx. $5.4 billion in 2022)
Structures destroyed: 17,500 buildings