Bordering the River Tiber’s west bank, upscale Prati is an art nouveau district anchored by Via Cola di Rienzo and its high-end boutiques. At night, the boulevards come to life with a mix of al fresco wine bars, stylish cocktail lounges, and gourmet restaurants. Showing big-name movies, Teatro Adriano sits close to imposing Castel Sant’Angelo, a circular, 2nd-century fortress with rooftop views over Vatican City.