Flanked by Vatican City and the Tiber River, Borgo is home to the sprawling 2nd-century Castel Sant’Angelo, which has panoramic city views and formal gardens. Busy streets are filled with relaxed cafes, bars, and sidewalk bistros, along with tourist hotels. Shops are concentrated along quaint cobblestone streets like Borgo Pio and Via della Conciliazione, also home to the popular Leonardo Da Vinci Experience Museum.