Costanza Farnese was a daughter of Alessandro Farnese and Silvia Ruffini. Born before her father became Pope Paul III, her siblings were Pier Luigi, Paul, Ranuccio and Lucrezia. Wikipedia
Born: December 19, 1500, Rome, Italy
Died: May 23, 1545 (age 44 years), Rome, Italy
Great grandchildren: Virginio Orsini, Duke of Bracciano, Donna Eleonora Orsini, Gregorio Boncompagni, II duca di Sora, and more
Parents: Pope Paul III and Silvia Ruffini
Grandchildren: Paolo Giordano I Orsini, Federico Sforza, Duca di Segni, Constanza Sforza, and more
Cousins: Laura Borgia and Laura Migliorati