In enzymology, a 1-pyrroline-5-carboxylate dehydrogenase is an enzyme that catalyzes the chemical reaction -1-pyrroline-5-carboxylate + NAD⁺ + 2 H₂O L-glutamate + NADH + H⁺ The three substrates of this enzyme are-1-pyrroline-5-carboxylate, NAD⁺,... Wikipedia