In enzymology, a 3-hydroxyacyl-CoA dehydrogenase is an enzyme that catalyzes the chemical reaction -3-hydroxyacyl-CoA + NAD⁺ \rightleftharpoons 3-oxoacyl-CoA + NADH + H⁺ Thus, the two substrates of this enzyme are-3-hydroxyacyl-CoA and NAD⁺,... Wikipedia