In enzymology, a succinate-semialdehyde dehydrogenase is an enzyme that catalyzes the chemical reaction succinate semialdehyde + NAD⁺ + H₂O ⇌ succinate + NADH + 2 H⁺ The 3 substrates of this enzyme are succinate semialdehyde, NAD⁺, and H₂O,... Wikipedia