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Triangle Shirtwaist Factory fire

Industrial disaster
The Triangle Shirtwaist Factory fire in the Greenwich Village neighborhood of Manhattan, New York City, on Saturday, March 25, 1911, was the deadliest industrial disaster in the history of the city, and one of the deadliest in U.S. history. Wikipedia
Number of deaths: 146
Date: March 25, 1911
Non-fatal injuries: 78