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Spanish flu

Pandemic
The 1918–1920 flu pandemic, also known as the Great Influenza epidemic or by the common misnomer Spanish flu, was an exceptionally deadly global influenza pandemic caused by the H1N1 influenza A virus. Wikipedia
Start date: February 1918
Deaths: 25–50 million (generally accepted), other estimates range from 17 to 100 million
End date: April 1920
Disease: Influenza
Suspected cases‡: 500 million (estimated)
Virus strain: Strains of A/H1N1